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1

Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity

Olga V. Belyaeva, Olga V. Korkina, Anton V. Stetsenko, Natalia Y. Kedishvili

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 259 KB

english, 2008

2

Coenzyme A- and NADH-dependent esterase activity of methylmalonate semialdehyde dehydrogenase

Kirill M. Popov, Natalia Y. Kedishvili, Robert A. Harris

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1992

Langue:

english

Fichier:

PDF, 622 KB

english, 1992

3

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative

Bengt Persson, Yvonne Kallberg, James E. Bray, Elspeth Bruford, Stephen L. Dellaporta, Angelo D. Favia, Roser Gonzalez Duarte, Hans Jörnvall, Kathryn L. Kavanagh, Natalia Kedishvili, Michael Kisiela,

Journal:

Chemico-Biological Interactions

Année:

2009

Langue:

english

Fichier:

PDF, 143 KB

english, 2009

4

Biochemical characterization of human epidermal retinol dehydrogenase 2

Seung-Ah Lee, Olga V. Belyaeva, Natalia Y. Kedishvili

Journal:

Chemico-Biological Interactions

Année:

2009

Langue:

english

Fichier:

PDF, 958 KB

english, 2009

5

Introduction

T. Geoffrey Flynn, Natalia Kedishvili, Edmund Maser, Peter J. O’Brien, Bryce V. Plapp

Journal:

Chemico-Biological Interactions

Année:

2011

Langue:

english

Fichier:

PDF, 86 KB

english, 2011

6

Evidence that proteosome inhibitors and chemical chaperones can rescue the activity of retinol dehydrogenase 12 mutant T49M

Seung-Ah Lee, Olga V. Belyaeva, Natalia Y. Kedishvili

Journal:

Chemico-Biological Interactions

Année:

2011

Langue:

english

Fichier:

PDF, 363 KB

english, 2011

7

Disease-associated variants of microsomal retinol dehydrogenase 12 (RDH12) are degraded at mutant-specific rates

Seung-Ah Lee, Olga V. Belyaeva, Natalia Y. Kedishvili

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 430 KB

english, 2010

8

Cloning of the human RoDH-related short chain dehydrogenase gene and analysis of its structure

Natalia Y. Kedishvili, Olga V. Belyaeva, Wendy H. Gough

Journal:

Chemico-Biological Interactions

Année:

2001

Langue:

english

Fichier:

PDF, 192 KB

english, 2001

9

Characterization of truncated mutants of human microsomal short-chain dehydrogenase/reductase RoDH-4

Olga V. Belyaeva, Sergei V. Chetyrkin, Natalia Y. Kedishvili

Journal:

Chemico-Biological Interactions

Année:

2003

Langue:

english

Fichier:

PDF, 344 KB

english, 2003

10

Cimetidine Inhibition of Human Gastric and Liver Alcohol Dehydrogenase Isoenzymes: Identification of Inhibitor Complexes by Kinetics and Molecular Modeling

Stone, Carol L., Hurley, Thomas D., Peggs, Cara F., Kedishvili, Natalia Y., Davis, Gerard J., Thomasson, Holly R., Li, Ting-Kai, Bosron, William F.

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 870 KB

english, 1995

11

Further Characterization of Human Microsomal 3α-Hydroxysteroid Dehydrogenase

Sergei V. Chetyrkin, Jiaping Hu, Wendy H. Gough, Natividad Dumaual, Natalia Y. Kedishvili

Journal:

Archives of Biochemistry and Biophysics

Année:

2001

Langue:

english

Fichier:

PDF, 310 KB

english, 2001

12

Effect of Cellular Retinol-Binding Protein on Retinol Oxidation by Human Class IV Retinol/Alcohol Dehydrogenase and Inhibition by Ethanol

Natalia Y. Kedishvili, Wendy H. Gough, Wilhelmina I. Davis, Steven Parsons, Ting-Kai Li, William F. Bosron

Journal:

Biochemical and Biophysical Research Communications

Année:

1998

Langue:

english

Fichier:

PDF, 116 KB

english, 1998

13

The effect of ligand binding on the proteolytic pattern of methylmalonate semialdehyde dehydrogenase

Natalia Y. Kedishvili, Kirill M. Popov, Robert A. Harris

Journal:

Archives of Biochemistry and Biophysics

Année:

1991

Langue:

english

Fichier:

PDF, 1.20 MB

english, 1991

14

Effect of lipid peroxidation products on the activity of human retinol dehydrogenase 12 (RDH12) and retinoid metabolism

Seung-Ah Lee, Olga V. Belyaeva, Natalia Y. Kedishvili

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2008

Langue:

english

Fichier:

PDF, 541 KB

english, 2008

15

Identification and characterization of retinoid-active short-chain dehydrogenases/reductases in Drosophila melanogaster

Olga V. Belyaeva, Seung-Ah Lee, Oleg V. Kolupaev, Natalia Y. Kedishvili

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

2009

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2009

16

Comparative genomic and phylogenetic analysis of short-chain dehydrogenases/reductases with dual retinol/sterol substrate specificity

Olga V. Belyaeva, Natalia Y. Kedishvili

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 939 KB

english, 2006

17

13-cis-Retinoic acid competitively inhibits 3α-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands?

Teresa Karlsson, Anders Vahlquist, Natalia Kedishvili, Hans Törmä

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 182 KB

english, 2003

18

Human pancreas protein 2 (PAN2) has a retinal reductase activity and is ubiquitously expressed in human tissues

Olga V Belyaeva, Natalia Y Kedishvili

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 133 KB

english, 2002

19

Molecular cloning of the branched-chain α-keto acid dehydrogenase kinase and the CoA-dependent methylmalonate semialdehyde dehydrogenase

Robert A. Harris, Kirill M. Popov, Natalia Y. Kedishvili, Yu Zhao, Yoshiharu Shimomura, Brett Robbins, David W. Crabb

Journal:

Advances in Enzyme Regulation

Année:

1993

Langue:

english

Fichier:

PDF, 1021 KB

english, 1993

20

[Methods in Enzymology] Branched-Chain Amino Acids, Part B Volume 324 || Mammalian Methylmalonate-Semialdehyde Dehydrogenase

Kedishvili, Natalia Y.

Année:

2000

Langue:

english

Fichier:

PDF, 914 KB

english, 2000

21

Introduction

Plapp, Bryce V., Kedishvili, Natalia Y., Rižner, Tea Lanišnik, Maser, Edmund, O’Brien, Peter J.

Journal:

Chemico-Biological Interactions

Année:

2013

Langue:

english

Fichier:

PDF, 128 KB

english, 2013

22

Activity And Membrane Binding Of Retinol Dehydrogenase-11 And Its Deletants

Audet, Marie-Lou, Methot, Mario, Beliaeva, Olga, Kedishvili, Natalia, Breton, Rock, Salesse, Christian

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 65 KB

english, 2009

23

Properties of Short-Chain Dehydrogenase/Reductase RalR1: Characterization of Purified Enzyme, Its Orientation in the Microsomal Membrane, and Distribution in Human Tissues and Cell Lines †

Belyaeva, Olga V., Stetsenko, Anton V., Nelson, Peter, Kedishvili, Natalia Y.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 137 KB

english, 2003

24

Differential Recognition of the Free versus Bound Retinol by Human Microsomal Retinol/Sterol Dehydrogenases: Characterization of the Holo-CRBP Dehydrogenase Activity of RoDH-4 †

Lapshina, Elena A., Belyaeva, Olga V., Chumakova, Olga V., Kedishvili, Natalia Y.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 125 KB

english, 2003

25

Biochemical Properties of Purified Human Retinol Dehydrogenase 12 (RDH12): Catalytic Efficiency toward Retinoids and C 9 Aldehydes and Effects of Cellular Retinol-Binding Protein Type I (CRBPI) and Cellular Retinaldehyde-Binding Protein (CRALBP) on the Oxidation and Reduction of Retinoids †

Belyaeva, Olga V., Korkina, Olga V., Stetsenko, Anton V., Kim, Tom, Nelson, Peter S., Kedishvili, Natalia Y.

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 210 KB

english, 2005

26

Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids

Gallego, Oriol, Belyaeva, Olga V., Porté, Sergio, Ruiz, F. Xavier, Stetsenko, Anton V., Shabrova, Elena V., Kostereva, Natalia V., Farrés, Jaume, Parés, Xavier, Kedishvili, Natalia Y.

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 308 KB

english, 2006

27

Evolutionary origins of retinoid active short-chain dehydrogenases/reductases of SDR16C family

Belyaeva, Olga V., Chang, Chenbei, Berlett, Michael C., Kedishvili, Natalia Y.

Journal:

Chemico-Biological Interactions

Année:

2015

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2015

28

Lipoprotein Particles of Intraocular Origin in Human Bruch Membrane: An Unusual Lipid Profile

Wang, Lan, Li, Chuan-Ming, Rudolf, Martin, Belyaeva, Olga V., Chung, Byung Hong, Messinger, Jeffrey D., Kedishvili, Natalia Y., Curcio, Christine A.

Journal:

Investigative Ophthalmology & Visual Science

Année:

2009

Langue:

english

Fichier:

PDF, 302 KB

english, 2009

29

Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers

Atigadda, Venkatram R., Xia, Gang, Deshpande, Anil, Wu, Lizhi, Kedishvili, Natalia, Smith, Craig D., Krontiras, Helen, Bland, Kirby I., Grubbs, Clinton J., Brouillette, Wayne J., Muccio, Donald D.

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.78 MB

english, 2015

30

Role of Microsomal Retinol/Sterol Dehydrogenase-Like Short-Chain Dehydrogenases/Reductases in the Oxidation and Epimerization of 3α-Hydroxysteroids in Human Tissues

Belyaeva, Olga V., Chetyrkin, Sergei V., Clark, Amy L., Kostereva, Natalia V., SantaCruz, Karen S., Chronwall, Bibie M., Kedishvili, Natalia Y.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 689 KB

english, 2007

31

Co-elimination and survival in gene network evolution: dismantling the RA-signaling in a chordate

Martí-Solans, Josep, Belyaeva, Olga V., Torres-Aguila, Nuria P., Kedishvili, Natalia Y., Albalat, Ricard, Cañestro, Cristian

Journal:

Molecular Biology and Evolution

Année:

2016

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2016

32

Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10

Adams, Mark K., Lee, Seung-Ah, Belyaeva, Olga V., Wu, Lizhi, Kedishvili, Natalia Y.

Journal:

Chemico-Biological Interactions

Année:

2016

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2016

33

The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all- trans -retinoic acid homeostasis

Belyaeva, Olga V., Adams, Mark K., Wu, Lizhi, Kedishvili, Natalia Y.

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2017

34

Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice

Belyaeva, Olga V., Wu, Lizhi, Shmarakov, Igor, Nelson, Peter S., Kedishvili, Natalia Y.

Journal:

Journal of Biological Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2018

35

Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

Wu, Lizhi, Chaudhary, Sandeep C., Atigadda, Venkatram R., Belyaeva, Olga V., Harville, Steven R., Elmets, Craig A., Muccio, Donald D., Athar, Mohammad, Kedishvili, Natalia Y., Schubert, Michael

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 6.68 MB

english, 2016

36

Tissue-specific kinase expression and activity regulates flux through the pyruvate dehydrogenase complex.

Klyuyeva, Alla, Tuganova, Alina, Kedishvili, Natalia Y., Popov, Kirill M

Journal:

Journal of Biological Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 953 KB

english, 2018

37

Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands

Wu, Lizhi, Belyaeva, Olga V., Adams, Mark K., Klyuyeva, Alla V., Lee, Seung-Ah, Goggans, Kelli R., Kesterson, Robert A., Popov, Kirill M., Kedishvili, Natalia Y.

Journal:

Journal of Biological Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 3.51 MB

english, 2019

38

Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands

Wu, Lizhi, Belyaeva, Olga V., Adams, Mark K., Klyuyeva, Alla V., Lee, Seung-Ah, Goggans, Kelli R., Kesterson, Robert A., Popov, Kirill M., Kedishvili, Natalia Y.

Journal:

Journal of Biological Chemistry

Année:

2019

Fichier:

PDF, 3.51 MB

2019

39

Generation of Retinaldehyde for Retinoic Acid Biosynthesis

Belyaeva, Olga V., Adams, Mark K., Popov, Kirill M., Kedishvili, Natalia Y.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2019

40

Generation of Retinaldehyde for Retinoic Acid Biosynthesis

Belyaeva, Olga V., Adams, Mark K., Popov, Kirill M., Kedishvili, Natalia Y.

Journal:

Année:

2019

Fichier:

PDF, 1.50 MB

2019

41

Vitamin A Metabolism During Refractory Telogen

Hovland, Damla, Suo, Liye, Kedishvili, Natalia, Sundberg, John, Everts, Helen

Journal:

Current Developments in Nutrition

Année:

2020

Fichier:

PDF, 74 KB

2020

42

Hsd17b13 Deficiency Does not Protect Mice From Obesogenic Diet Injury

Ma, Yanling, Brown, Philip M., Lin, Dennis D., Ma, Jing, Feng, Dechun, Belyaeva, Olga V., Podszun, Maren C., Roszik, Jason, Allen, Joselyn, Umarova, Regina, Kleiner, David E., Kedishvili, Natalia Y.,

Journal:

Année:

2020

Fichier:

PDF, 17.40 MB

2020

43

Characterization of Essential Domains in HSD17B13 for Cellular Localization and Enzymatic Activity

Ma, Yanling, Karki, Suman, Brown, Philip M., Lin, Dennis D., Podszun, Maren C., Zhou, Wenchang, Belyaeva, Olga V., Kedishvili, Natalia Y., Rotman, Yaron

Journal:

The Journal of Lipid Research

Année:

2020

Fichier:

PDF, 2.84 MB

2020